Advanced Therapies Production Unit

Phone: +390882 456565

Head of Lab: Dr. Daniela Celeste Profico


About Us

Introduction: UPTA – Advanced Therapies Production Unit, is a cell factory in compliance with the European Directive 2001/83/CE. The Unit has been authorized by the Italian Medicine Agency to produce human neural stem cells for experimental clinical trials (aM 118/2019).

UPTA also performs research activities aimed at the development of new therapeutic strategies for neurodegenerative diseases.

Studied Pathologies: Amyotrophic Lateral Sclerosis, Multiple Sclerosis


Head of the Lab

Name: Daniela Celeste Profico

University and Training: Degree in Medical Biotechnology obtained at the University of Teramo in 2008. Authorization as Qualified Person granted from the Italian Drug Agency in 2013. Master’s degree in Preclinical and Clinical Research obtained at University of Parma in 2021.

Work Experience: From 2008 to 2013 Head of Production at “Laboratorio Cellule Staminali, Cell Factory e Biobanca” of S. Maria Hospital in Terni.

Scientific Area of Interest: Production and characterization of advanced therapies medicinal products, development of new drugs for neurodegenerative diseases.
Collaborations: University Milano Bicocca, Laboratorio Cellule Staminali, Cell Factory e Biobanca (AOSP S. Maria, Terni)


Abate Lucrezia

D’Aloisio Giada

Gelati Maurizio

Mormone Elisabetta

Dott.ssa Ripoli Maria


Total list of Publications from 2011: n.8

Ongoing Research Projects

Start Year: 2021
Expiry: 2023
Funding Entity: Ministero Sviluppo Economico
Project Leader: Prof. Angelo Luigi Vescovi
Principal Investigator: Dr. Daniela Celeste Profico
Project Team: D’Aloisio Giada, Gelati Maurizio, Mormone Elisabetta, Ripoli Maria


Start Year: 2022
Expiry: 2024
Funding Entity: Ministero della Salute
Project Leader: Prof. Angelo Luigi Vescovi
Principal Investigator: Dr. Daniela Celeste Profico, Maurizio Gelati
Project Team: Abate Lucrezia, D’Aloisio Giada, Mormone Elisabetta, Ripoli Maria