Di Paola Rosa

Rosa Di Paola studia i meccanismi molecolari che contribuiscono allo sviluppo dell'insulino-resistenza e del diabete di tipo 2. Coordina progetti focalizzati su inibitori del segnale e dell'azione insulinica combinando approcci di genetica e di fisiologia molecolare.

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Informazioni aggiuntive

  • Pubblicazioni Scientifiche:

    Totale pubblicazioni a partire dal 2011: 28


    Anno

    2019; (): e728

    Association of a homozygous GCK missense mutation with mild diabetes.

    Marucci A, Biagini T, Di Paola R, Menzaghi C, Fini G, Castellana S, Cardinale GM, Mazza T, Trischitta V


    2018; 122(5): 910

    Is There Really a Paradoxical Effect of Obesity on Mortality Rate in High-Risk Patients? It Is Time for Large Mendelian Randomization Studies.

    Trischitta V, Di Paola R


    2017; 27(4): 281-282

    GALNT2 effect on HDL-cholesterol and triglycerides levels in humans: Evidence of pleiotropy?

    Di Paola R, Marucci A, Trischitta V


    2017; ():

    Pharmacogenetics of oral antidiabetes drugs: evidence for diverse signals at the IRS1 locus.

    Prudente S, Di Paola R, Pezzilli S, Garofolo M, Lamacchia O, Filardi T, Mannino GC, Mercuri L, Alberico F, Scarale MG, Sesti G, Morano S, Penno G, Cignarelli M, Copetti M, Trischitta V


    2017; 7(): 44337

    Suggestive evidence of a multi-cytokine resistin pathway in humans and its role on cardiovascular events in high-risk individuals.

    Menzaghi C, Marucci A, Antonucci A, De Bonis C, Ortega Moreno L, Salvemini L, Copetti M, Trischitta V, Di Paola R


    2016; 59 (suppl 1): S512

    Role of the "resistin pathway" on cardiovascular risk factors and major cardiovascular events

    Menzaghi C., Marucci A., Antonucci A., De Bonis C., Ortega Moreno L., Salvemini L., Copetti M., Trischitta V., Di Paola R.

    2016; 59(Suppl1): S1-S581

    UMOD locus and glomerular filtration rate in individuals with type 2 diabetes: evidence of heterogeneity across two different European populations

    Prudente S., Di Paola R., Copetti M., Lucchesi D., Lamacchia O., Pezzilli S., Mercuri L., Alberico F., GIusti L., Garofalo M., Penno G., Cignarelli M., De Cosmo S., Trischitta V.

    2016; ():

    The rs12917707 polymorphism at the UMOD locus and glomerular filtration rate in individuals with type 2 diabetes: evidence of heterogeneity across two different European populations.

    Prudente S, Di Paola R, Copetti M, Lucchesi D, Lamacchia O, Pezzilli S, Mercuri L, Alberico F, Giusti L, Garofolo M, Penno G, Cignarelli M, De Cosmo S, Trischitta V


    Il Diabete, Supp.I, 2016, P192 2016; : 93

    Ruolo del polimorfismo rs12917707 nel gene UMOD nella modulazione del GFR in pazienti italiani con diabete di tipo 2

    Pezzilli S., Di Paola R., Copetti M., Lucchesi D., La Macchia O., Mercuri L., Alberico F., Pucci L., Penno G., Cignarelli M., De Cosmo S., Trischitta V., Prudente S.

    2015; ():

    Strong evidence of sexual dimorphic effect of adiposity excess on insulin sensitivity.

    Marucci A, Menzaghi C, Copetti M, Vinciguerra F, Baratta R, Salvemini L, Morini E, Frittitta L, Di Paola R, Trischitta V


    2015; ():

    GALNT2 mRNA levels are associated with serum triglycerides in humans.

    Marucci A, Mangiacotti D, Trischitta V, Di Paola R


    2015; ():

    Loss-of-Function Mutations in APPL1 in Familial Diabetes Mellitus.

    Prudente S, Jungtrakoon P, Marucci A, Ludovico O, Buranasupkajorn P, Mazza T, Hastings T, Milano T, Morini E, Mercuri L, Bailetti D, Mendonca C, Alberico F, Basile G, Romani M, Miccinilli E, Pizzuti A, Carella M, Barbetti F, Pascarella S, Marchetti P, Tri


    2014; ():

    Sex-specific effect of BMI on insulin sensitivity and TNF-? expression.

    Marucci A, Mangiacotti D, di Mauro L, Antonacci M, Trischitta V, Di Paola R


    2014; 37(12): e258-60

    Low Prevalence of HNF1A Mutations After Molecular Screening of Multiple MODY Genes in 58 Italian Families Recruited in the Pediatric or Adult Diabetes Clinic From a Single Italian Hospital.

    Delvecchio M, Ludovico O, Menzaghi C, Di Paola R, Zelante L, Marucci A, Grasso V, Trischitta V, Carella M, Barbetti F


    2014; 40(): 58

    Clinical heterogeneity of abnormal glucose homeostasis associated with the HNF4A R311H mutation.

    Delvecchio M, Di Paola R, Mangiacotti D, Sacco M, Menzaghi C, Trischitta V


    2014; 63 (S1): 136 OR

    Mutations in the APPL1 Gene May Contribute to Familial Diabetes

    Prudente S., Prapaporn J., Marucci A., Ludovico O., Mazza T., Hastings T., Morini E., Mercuri L., Bailetti D., Mendonca C., Alberico F., Basile G., Romani M., Miccinilli E., Carella M., Barbetti F., Trischitta V., Di Paola R., Doria A..

    2014; 57: S154

    Mutations in APPL1 gene may contribute to familial diabetes mellitus

    Prudente S., Prapaporn J., Marucci A., Ludovico O., Mazza T., Hastings T., Mercuri L., Bailetti D., Mendonca C., Carella M., Barbetti F., Trischitta V., Di Paola R., Doria A.

    2013; 36(9): 2830-5

    Development and validation of a predicting model of all-cause mortality in patients with type 2 diabetes.

    De Cosmo S, Copetti M, Lamacchia O, Fontana A, Massa M, Morini E, Pacilli A, Fariello S, Palena A, Rauseo A, Viti R, Di Paola R, Menzaghi C, Cignarelli M, Pellegrini F, Trischitta V


    2013; 5: S172

    Evidence of reverse epidemiology between obesity and all-cause mortality in whites with type 2 diabetes from Italy

    Di Paola R., Marucci A., Fontana A., Menzaghi C., Salvemini L., Copetti M., Pellegrini F., De Cosmo S., Trischitta V.

    2013; ():

    Role of obesity on all-cause mortality in whites with type 2 diabetes from Italy.

    Di Paola R, Marucci A, Fontana A, Menzaghi C, Salvemini L, Copetti M, Pellegrini F, De Cosmo S, Trischitta V


    2013; 8(7): e70159

    GALNT2 Expression Is Reduced in Patients with Type 2 Diabetes: Possible Role of Hyperglycemia.

    Marucci A, di Mauro L, Menzaghi C, Prudente S, Mangiacotti D, Fini G, Lotti G, Trischitta V, Di Paola R


    2013; 1833(6): 1388-95

    Role of GALNT2 in the modulation of ENPP1 expression, and insulin signaling and action: GALNT2: a novel modulator of insulin signaling.

    Marucci A, Cozzolino F, Dimatteo C, Monti M, Pucci P, Trischitta V, Di Paola R


    2013; :

    Development and validation of a predicting model of all-cause mortality in patients with type 2 diabetes mellitus

    De Cosmo S, Copetti M, Lamacchia O, Fontana A, Michela M, Morini E, Pacilli A, Fariello S, Palena A, Rauseo A, Viti R, Di Paola R, Menzaghi C, Cignarelli M, Pellegrini F, Trischitta V,

    2012; ():

    Role of somatomedin-B-like domains on ENPP1 inhibition of insulin signaling.

    Dimatteo C, Marucci A, Palazzo A, Cisternino C, Marsano RM, Trischitta V, Di Paola R


    2012; 226(1): 140-5

    Joint effect of insulin signaling genes on cardiovascular events and on whole body and endothelial insulin resistance.

    Bacci S, Prudente S, Copetti M, Spoto B, Rizza S, Baratta R, Di Pietro N, Morini E, Di Paola R, Testa A, Mallamaci F, Tripepi G, Zhang YY, Mercuri L, Di Silvestre S, Lauro R, Malatino L, Consoli A, Pellegrini F, Pandolfi A, Frittitta L, Zoccali C, Federic


    2012; 7(6): e38414

    Serum resistin and kidney function: a family-based study in non-diabetic, untreated individuals.

    Menzaghi C, Salvemini L, Fini G, Thompson R, Mangiacotti D, Di Paola R, Morini E, Giorelli M, De Bonis C, De Cosmo S, Doria A, Trischitta V


    2011; 6(5): e19462

    ENPP1 affects insulin action and secretion: evidences from in vitro studies.

    Di Paola R, Caporarello N, Marucci A, Dimatteo C, Iadicicco C, Del Guerra S, Prudente S, Sudano D, Miele C, Parrino C, Piro S, Beguinot F, Marchetti P, Trischitta V, Frittitta L


    2011; ():

    PPAR?2 P12A polymorphism and albuminuria in patients with type 2 diabetes: a meta-analysis of case-control studies.

    De Cosmo S, Prudente S, Lamacchia O, Lapice E, Morini E, Di Paola R, Copetti M, Ruggenenti P, Remuzzi G, Vaccaro O, Cignarelli M, Trischitta V


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