Palmieri Orazio

E' coinvolto negli studi di genetica e farmacogenetica delle malattie infiammatorie croniche intestinali (MICI) e della genetica dell'acalasia.
Responsabile della progettazione e della messa a punto delle metodiche di genotipizzazione dei polimorfismi genetici, dell'espressione e co-espressione di geni e di miRNA, della gestione e dell'analisi preliminare dei dati.

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Informazioni aggiuntive

  • Pubblicazioni Scientifiche:

    Totale pubblicazioni a partire dal 2011: 55


    Anno

    2018; 14(5): e1007329

    Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population.

    Rivas MA, Avila BE, Koskela J, Huang H, Stevens C, Pirinen M, Haritunians T, Neale BM, Kurki M, Ganna A, Graham D, Glaser B, Peter I, Atzmon G, Barzilai N, Levine AP, Schiff E, Pontikos N, Weisburd B, Lek M, Karczewski KJ, Bloom J, Minikel EV, Petersen BS


    2018; 8(1): 16389

    Droplet digital PCR quantification of miR-1290 as a circulating biomarker for pancreatic cancer.

    Tavano F, Gioffreda D, Valvano MR, Palmieri O, Tardio M, Latiano TP, Piepoli A, Maiello E, Pirozzi F, Andriulli A


    2018; 9(1): 2427

    IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes.

    Momozawa Y, Dmitrieva J, Théâtre E, Deffontaine V, Rahmouni S, Charloteaux B, Crins F, Docampo E, Elansary M, Gori AS, Lecut C, Mariman R, Mni M, Oury C, Altukhov I, Alexeev D, Aulchenko Y, Amininejad L, Bouma G, Hoentjen F, Löwenberg M, Oldenburg B, P


    2017; 153(2): 550-565

    Genetic Factors Interact With Tobacco Smoke to Modify Risk for Inflammatory Bowel Disease in Humans and Mice.

    Yadav P, Ellinghaus D, Rémy G, Freitag-Wolf S, Cesaro A, Degenhardt F, Boucher G, Delacre M, International IBD Genetics Consortium., Peyrin-Biroulet L, Pichavant M, Rioux JD, Gosset P, Franke A, Schumm LP, Krawczak M, Chamaillard M, Dempfle A, Andersen V


    2017; 49(2): 269-273

    Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease.

    Ji SG, Juran BD, Mucha S, Folseraas T, Jostins L, Melum E, Kumasaka N, Atkinson EJ, Schlicht EM, Liu JZ, Shah T, Gutierrez-Achury J, Boberg KM, Bergquist A, Vermeire S, Eksteen B, Durie PR, Farkkila M, Müller T, Schramm C, Sterneck M, Weismüller TJ, Got


    2017; 18(1): 94

    Performance of risk prediction for inflammatory bowel disease based on genotyping platform and genomic risk score method.

    Chen GB, Lee SH, Montgomery GW, Wray NR, Visscher PM, Gearry RB, Lawrance IC, Andrews JM, Bampton P, Mahy G, Bell S, Walsh A, Connor S, Sparrow M, Bowdler LM, Simms LA, Krishnaprasad K, International IBD Genetics Consortium., Radford-Smith GL, Moser G


    2017; 547(7662): 173-178

    Fine-mapping inflammatory bowel disease loci to single-variant resolution.

    Huang H, Fang M, Jostins L, Umicevic Mirkov M, Boucher G, Anderson CA, Andersen V, Cleynen I, Cortes A, Crins F, D'Amato M, Deffontaine V, Dmitrieva J, Docampo E, Elansary M, Farh KK, Franke A, Gori AS, Goyette P, Halfvarson J, Haritunians T, Knight J, La


    2017; 18(7):

    Functional Implications of MicroRNAs in Crohn's Disease Revealed by Integrating MicroRNA and Messenger RNA Expression Profiling.

    Palmieri O, Creanza TM, Bossa F, Latiano T, Corritore G, Palumbo O, Martino G, Biscaglia G, Scimeca D, Carella M, Ancona N, Andriulli A, Latiano A


    2017; 12(1): e0168821

    Crohn's Disease Localization Displays Different Predisposing Genetic Variants.

    Palmieri O, Bossa F, Valvano MR, Corritore G, Latiano T, Martino G, D'Incà R, Cucchiara S, Pastore M, D'Altilia M, Scimeca D, Biscaglia G, Andriulli A, Latiano A


    OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY 2016; 20(12): 692-698

    Inflammatory Bowel Disease Meets Systems Biology: A Multi-Omics Challenge and Frontier.

    Palmieri O, Mazza T, Castellana S, Panza A, Latiano T, Corritore G, Andriulli A, Latiano A


    2016; :

    Inflammatory Bowel Disease Meets Systems Biology: A Multi-Omics Challenge and Frontier

    Palmieri O., Mazza T., Castellana S., Panza A., Latiano T., Corritore G., Andriulli A., Latiano A.

    2016; :

    A Polymorphism of the Tnf-? Gene Promotes Steroid-Resistance In patients with Inflammatory Bowel Disease

    Palmieri O., Latiano A., Bossa F., Valvano M.R., D'incà R., Corritore G., Latiano T., Andriulli A., Annese V.

    2016; ():

    Efficacy and Safety of Long-Term Administration of Tapentadol in Relieving Chronic Pancreatitis Pain.

    Iacobellis A, Seripa D, Palmieri O, Andriulli N, Latina P


    2016; 6(): 31549

    Gene expression of muscular and neuronal pathways is cooperatively dysregulated in patients with idiopathic achalasia.

    Palmieri O, Mazza T, Merla A, Fusilli C, Cuttitta A, Martino G, Latiano T, Corritore G, Bossa F, Palumbo O, Muscarella LA, Carella M, Graziano P, Andriulli A, Latiano A


    2016; ():

    Vitamin D receptor gene polymorphisms/haplotypes and serum 25(OH)D3 levels in Hashimoto's thyroiditis.

    Giovinazzo S, Vicchio TM, Certo R, Alibrandi A, Palmieri O, Campennì A, Cannavò S, Trimarchi F, Ruggeri RM


    2016; ():

    Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.

    Ellinghaus D, Jostins L, Spain SL, Cortes A, Bethune J, Han B, Park YR, Raychaudhuri S, Pouget JG, Hübenthal M, Folseraas T, Wang Y, Esko T, Metspalu A, Westra HJ, Franke L, Pers TH, Weersma RK, Collij V, D'Amato M, Halfvarson J, Jensen AB, Lieb W, Degenh


    2015; : e257

    Whole exome sequencing of very early onset ulcerative colitis patients identifies new variants in candidate genes

    Palmieri O., Aloi M., Prudente S., Mazza T., Stronati L., Corritore G., Latiano T., Bossa F., Andriulli A., Cucchiara S., Latiano A.

    2015; ():

    Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study.

    Cleynen I, Boucher G, Jostins L, Schumm LP, Zeissig S, Ahmad T, Andersen V, Andrews JM, Annese V, Brand S, Brant SR, Cho JH, Daly MJ, Dubinsky M, Duerr RH, Ferguson LR, Franke A, Gearry RB, Goyette P, Hakonarson H, Halfvarson J, Hov JR, Huang H, Kennedy N


    2015; 47(9): 979-86

    Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations.

    Liu JZ, van Sommeren S, Huang H, Ng SC, Alberts R, Takahashi A, Ripke S, Lee JC, Jostins L, Shah T, Abedian S, Cheon JH, Cho J, Daryani NE, Franke L, Fuyuno Y, Hart A, Juyal RC, Juyal G, Kim WH, Morris AP, Poustchi H, Newman WG, Midha V, Orchard TR, Vahed


    2015; (): 1-14

    Systematic analysis of circadian genes using genome-wide cDNA microarrays in the inflammatory bowel disease transcriptome.

    Palmieri O, Mazzoccoli G, Bossa F, Maglietta R, Palumbo O, Ancona N, Corritore G, Latiano T, Martino G, Rubino R, Biscaglia G, Scimeca D, Carella M, Annese V, Andriulli A, Latiano A


    2015; ():

    Genome-wide Pathway Analysis Using Gene Expression Data of Colonic Mucosa in Patients with Inflammatory Bowel Disease.

    Palmieri O, Creanza TM, Bossa F, Palumbo O, Maglietta R, Ancona N, Corritore G, Latiano T, Martino G, Biscaglia G, Scimeca D, De Petris MP, Carella M, Annese V, Andriulli A, Latiano A


    2015; 47(2): 172-9

    High-density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis.

    Goyette P, Boucher G, Mallon D, Ellinghaus E, Jostins L, Huang H, Ripke S, Gusareva ES, Annese V, Hauser SL, Oksenberg JR, Thomsen I, Leslie S, International Inflammatory Bowel Disease Genetics Consortium, Australia and New Zealand IBDGC, Belgium IBD Gene


    2014; 34(9): 1369-77

    Variation in genes encoding for interferon ?-3 and ?-4 in the prediction of HCV-1 treatment-induced viral clearance.

    Palmieri O, Ippolito AM, Margaglione M, Valvano MR, Gioffreda D, Fasano M, D'Andrea G, Corritore G, Milella M, Andriulli N, Morisco F, Giannitrapani L, Latiano A, Fontana R, Gatti P, Tundo P, Barone M, Cozzolongo R, Santantonio T, Andriulli A


    2014; 94(3): 437-52

    An excess of risk-increasing low-frequency variants can be a signal of polygenic inheritance in complex diseases.

    Chan Y, Lim ET, Sandholm N, Wang SR, McKnight AJ, Ripke S, DIAGRAM Consortium, GENIE Consortium, GIANT Consortium, IIBDGC Consortium, PGC Consortium, Daly MJ, Neale BM, Salem RM, Hirschhorn JN


    2014; ():

    Reply to "Triple or dual therapy for HCV-1 naive patients? Optimizing selection tools"

    Palmieri O, Valvano MR, Margaglione M, Andriulli A


    2014; ():

    Feasibility of pegylated interferon and ribavirin in hepatitis C-related cirrhosis with neutropenia or thrombocytopenia.

    Iacobellis A, Cozzolongo R, Minerva N, Valvano MR, Niro GA, Fontana R, Palmieri O, Ippolito A, Andriulli A


    2014; ():

    Can we include genetic variants with high linkage disequilibrium into a multiple logistic model? Author's reply.

    Palmieri O, Valvano MR


    2014; 75(4): 364-9

    Impact of genetic polymorphisms on the pathogenesis of idiopathic achalasia: Association with IL33 gene variant.

    Latiano A, Palmieri O, Bossa F, Latiano T, Corritore G, De Santo E, Martino G, Merla A, Valvano MR, Cuttitta A, Mazza T, Annese V, Andriulli A


    XVI Congresso Nazionale SIGU 2013; : P273

    Identification of naïve HCV-1 patients with chronic hepatitis who may benefit from dual therapy with peg-interferon and ribavirin

    Palmieri O., D'andrea G., De Girolamo G., Di Marco V., Margaglione M., Ippolito A.M., Fattovich G., Smedile A., Valvano M.R., Calvaruso V., Gioffreda D., Milella M., Morisco F., Felder M., Brancaccio G., Fasano M., Gatti P., Tundo P., Barone M., Cozzolong

    2013; : S-471

    Genetic Risk Profiling of Complicated Disease Course in Crohn's Disease Patients

    Latiano A., Palmieri O., Buccianti N., Scimeca D., Biscaglia G., Valvano M.R., D'Incà R., Annese V., Andriulli A.

    2013; 45(12): 1003-10

    Genetic variants of membrane metallopeptidase genes in inflammatory bowel diseases.

    Tavano F, Palmieri O, di Mola FF, Latiano A, Burbaci FP, Valvano MR, Corritore G, Augello B, Merla G, Annese V, Andriulli A, di Sebastiano P


    Società Italiana di Genetica Umana - XVI Congresso Nazionale 2013; : P321

    The TT/-G frameshift variant of the novel IFNL4 gene not improves HCV1 clearance prediction

    Palmieri O., D'andrea G. , Ippolito A.M., De Girolamo G. , Margaglione M., Latiano A., Valvano M.R., Gioffreda D., Fasano M., Milella M., Morisco F., Montalto G., Gatti P., Tundo P., Barone M., Cozzolongo R., Santantonio T., Andriulli A.

    2013; ():

    Genetic variation in the lymphotoxin-? (LTA)/tumour necrosis factor-? (TNF?) locus as a risk factor for idiopathic achalasia.

    Wouters MM, Lambrechts D, Becker J, Cleynen I, Tack J, Vigo AG, Ruiz de León A, Urcelay E, Pérez de la Serna J, Rohof W, Annese V, Latiano A, Palmieri O, Mattheisen M, Mueller M, Lang H, Fumagalli U, Laghi L, Zaninotto G, Cuomo R, Sarnelli G, Nöthen MM, V


    2013; 19(9): 1872-9

    Erythrocytes-mediated Delivery of Dexamethasone 21-phosphate in Steroid-dependent Ulcerative Colitis: A Randomized, Double-blind Sham-controlled Study.

    Bossa F, Annese V, Valvano MR, Latiano A, Martino G, Rossi L, Magnani M, Palmieri O, Serafini S, Damonte G, De Santo E, Andriulli A


    2013; 45(6): 670-5

    Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis.

    Liu JZ, Hov JR, Folseraas T, Ellinghaus E, Rushbrook SM, Doncheva NT, Andreassen OA, Weersma RK, Weismüller TJ, Eksteen B, Invernizzi P, Hirschfield GM, Gotthardt DN, Pares A, Ellinghaus D, Shah T, Juran BD, Milkiewicz P, Rust C, Schramm C, Müller T, Sriv


    2013; 8(4): e62144

    Associations between Genetic Polymorphisms in IL-33, IL1R1 and Risk for Inflammatory Bowel Disease.

    Latiano A, Palmieri O, Pastorelli L, Vecchi M, Pizarro TT, Bossa F, Merla G, Augello B, Latiano T, Corritore G, Settesoldi A, Valvano MR, D'Incà R, Stronati L, Annese V, Andriulli A


    2013; 27(1): 9-22

    Transcriptional regulators, the circadian clock and the immune system.

    Vinciguerra M, Borghesan M, Pazienza V, Piepoli A, Palmieri O, Tarquini R, Tevy MF, De Cata A, Mazzoccoli G


    2013; 2013 - suppl 1: s 278 - p667

    Dissecting the role of unfolded protein response pathway in inflammatory bowel disease: in silico mRNA-miRNA co-expression analysis

    Palmieri O, Bossa F, Creanza MT, Latiano T, Corritore G, Scimeca D, Biscaglia G, Liuzzi VC, Anglani R, Carella M, Annese V, Andriulli A, Latiano A

    2012; 491(7422): 119-24

    Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.

    Jostins L, Ripke S, Weersma RK, Duerr RH, McGovern DP, Hui KY, Lee JC, Schumm LP, Sharma Y, Anderson CA, Essers J, Mitrovic M, Ning K, Cleynen I, Theatre E, Spain SL, Raychaudhuri S, Goyette P, Wei Z, Abraham C, Achkar JP, Ahmad T, Amininejad L, Ananthakr


    2012; 31(4): 731-40

    TOMM40, APOE, and APOC1 in Primary Progressive Aphasia and Frontotemporal Dementia.

    Seripa D, Bizzarro A, Pilotto A, Palmieri O, Panza F, D'Onofrio G, Gravina C, Archetti S, Daniele A, Borroni B, Padovani A, Masullo C


    2012; 237(10): 1123-8

    The expression of leucine-rich repeat gene family members in colorectal cancer.

    Piepoli A, Palmieri O, Maglietta R, Panza A, Cattaneo E, Latiano A, Laczko E, Gentile A, Carella M, Mazzoccoli G, Ancona N, Marra G, Andriulli A


    2012; 29(8): 994-1003

    Association Study of a Polymorphism in Clock Gene PERIOD3 and Risk of Inflammatory Bowel Disease.

    Mazzoccoli G, Palmieri O, Corritore G, Latiano T, Bossa F, Scimeca D, Biscaglia G, Valvano MR, D'Incà R, Cucchiara S, Stronati L, Annese V, Andriulli A, Latiano A


    2012; 6-p448: s187

    Polymorphism in IL-33, IL1RL1 genes and risk of inflammatory bowel disease

    Latiano A, Palmieri O, Pastorelli L, Vecchi M, Pizarro T, Bossa F, Merla G, Augello B, Valvano MR, D'Incà R, Cucchiara S, Annese V, Andriulli A,

    2012; 6(5): 563-70

    Neuroimmune interactions in patients with inflammatory bowel diseases: Disease activity and clinical behavior based on Substance P serum levels.

    Tavano F, di Mola FF, Latiano A, Palmieri O, Bossa F, Valvano MR, Latiano T, Annese V, Andriulli A, di Sebastiano P


    2012; 90(4): 636-47

    Combined Analysis of Genome-wide Association Studies for Crohn Disease and Psoriasis Identifies Seven Shared Susceptibility Loci.

    Ellinghaus D, Ellinghaus E, Nair RP, Stuart PE, Esko T, Metspalu A, Debrus S, Raelson JV, Tejasvi T, Belouchi M, West SL, Barker JN, Kõks S, Kingo K, Balschun T, Palmieri O, Annese V, Gieger C, Wichmann HE, Kabesch M, Trembath RC, Mathew CG, Abecasis GR,


    2011; ():

    Glucocorticoid resistance in Crohn's disease and ulcerative colitis: an association study investigating GR and FKBP5 gene polymorphisms.

    Maltese P, Palma L, Sfara C, de Rocco P, Latiano A, Palmieri O, Corritore G, Annese V, Magnani M


    2011; 43(11): 1066-73

    Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease.

    Rivas MA, Beaudoin M, Gardet A, Stevens C, Sharma Y, Zhang CK, Boucher G, Ripke S, Ellinghaus D, Burtt N, Fennell T, Kirby A, Latiano A, Goyette P, Green T, Halfvarson J, Haritunians T, Korn JM, Kuruvilla F, Lagacé C, Neale B, Lo KS, Schumm P, Törkvist


    2011; AGA Abstracts: S-272

    Dissection of the Crohn's Disease Transcriptome of 71 Loci Using Genome-Wide Microarrays

    Orazio Palmieri, Anna Latiano, Rosalia Maglietta, Orazio Palumbo, Giuseppe Corritore, Tiziana Latiano, Giuseppina Martino, Massimo Carella, Nicola Ancona, Fabrizio Bossa, Angelo Andriulli, Vito Annese

    2011; : S161

    Whole-transcript human gene expression pathway analysis in Crohn's disease

    O. Palmieri, A. Latiano, R. Maglietta, B. Fabrizio, D. Scimeca, G. Biscaglia, O. Palumbo, M. Carella, N. Ancona, A. Andriulli, V. Annese

    2011; ():

    Discovering genetic variants in Crohn's disease by exploring genomic regions enriched of weak association signals.

    D'Addabbo A, Palmieri O, Maglietta R, Latiano A, Mukherjee S, Annese V, Ancona N


    2011; 12(): 166

    RS-SNP: a random-set method for genome-wide association studies.

    D'Addabbo A, Palmieri O, Latiano A, Annese V, Mukherjee S, Ancona N


    2011; ():

    IL23R, ATG16L1, IRGM, OCTN1, and OCTN2 mRNA expression in inflamed and noninflamed mucosa of IBD patients.

    Palmieri O, Latiano A, Scimeca D, Bossa F, Corritore G, Latiano T, Andriulli A, Annese V


    2011; ():

    Dissecting the mucosal expression of human leucine-rich repeat family genes in inflammatory bowel disease patients.

    Palmieri O, Latiano A, Maglietta R, Palumbo O, Carella M, Ancona N, Bossa F, Andriulli A, Annese V


    2011; 7(1): e1001283

    A meta-analysis of genome-wide association scans identifies IL18RAP, PTPN2, TAGAP, and PUS10 as shared risk loci for Crohn's disease and celiac disease.

    Festen EA, Goyette P, Green T, Boucher G, Beauchamp C, Trynka G, Dubois PC, Lagacé C, Stokkers PC, Hommes DW, Barisani D, Palmieri O, Annese V, van Heel DA, Weersma RK, Daly MJ, Wijmenga C, Rioux JD


    2011; 43(3): 246-52

    Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47.

    Anderson CA, Boucher G, Lees CW, Franke A, D'Amato M, Taylor KD, Lee JC, Goyette P, Imielinski M, Latiano A, Lagacé C, Scott R, Amininejad L, Bumpstead S, Baidoo L, Baldassano RN, Barclay M, Bayless TM, Brand S, Büning C, Colombel JF, Denson LA, De Vos M,


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