1. Different states of stemness of glioblastoma stem cells sustain glioblastoma subtypes indicating novel clinical biomarkers and high-efficacy customized therapies.
 Visioli A, Trivieri N, Mencarelli G, Giani F, Copetti M, Palumbo O, Pracella R, Cariglia MG, Barile C, Mischitelli L, Soriano AA, Palumbo P, Legnani F, DiMeco F, Gorgoglione L, Pesole G, Vescovi AL, Binda E.J Exp Clin Cancer Res. 2023 Sep 21;42(1):244. doi: 10.1186/s13046-023-02811-0.PMID: 37735434 Free PMC article.

2. Local delivery of hrBMP4 as an anticancer therapy in patients with recurrent glioblastoma: a first-in-human phase 1 dose escalation trial.
 Bos EM,* Binda E*, Verploegh ISC, Wembacher E, Hoefnagel D, Balvers RK, Korporaal AL, Conidi A, Warnert EAH, Trivieri N, Visioli A, Zaccarini P, Caiola L, van Wijck R, van der Spek P, Huylebroeck D, Leenstra S, Lamfers MLM, Ram Z, Westphal M, Noske D, Legnani F, DiMeco F, Vescovi AL, Dirven CMF.Mol Cancer. 2023 Aug 10;22(1):129. doi: 10.1186/s12943-023-01835-6.PMID: 37563568 Free PMC article. *co-first authors

3. Changes in gut microbiota composition after 12 weeks of a home-based lifestyle intervention in breast cancer survivors during the COVID-19 lockdown.
 Donati Zeppa S, Natalucci V, Agostini D, Vallorani L, Amatori S, Sisti D, Rocchi MBL, Pazienza V, Perri F, Villani A, Binda E, Panebianco C, Mencarelli G, Ciuffreda L, Ferri Marini C, Annibalini G, Lucertini F, Bartolacci A, Imperio M, Virgili E, Catalano V, Piccoli G, Stocchi V, Emili R, Barbieri E.Front Oncol. 2023 Sep 1;13:1225645. doi: 10.3389/fonc.2023.1225645. eCollection 2023.PMID: 37727203 Free PMC article.

4. Simone L, Pisani F, Binda E, Frigeri A, Vescovi AL, Svelto M, Nicchia GP. “AQP4-dependent glioma cell features affect the phenotype of surrounding cells via extracellular vesicles.” (2022) Cell Biosci Sep 7;12(1):150. doi: 10.1186/s13578-022-00888-2. PMID: 36071478

5. Turco EM, Giovenale AMG, Sireno L, Mazzoni M, Cammareri A, Marchioretti C, Goracci L, Di Veroli A, Marchesan E, D'Andrea D, Falconieri A, Torres B, Bernardini L, Magnifico MC, Paone A, Rinaldo S, Della Monica M, D'Arrigo S, Postorivo D, Nardone AM, Zampino G, Onesimo R, Leoni C, Caicci F, Raimondo D, Binda E, Trobiani L, De Jaco A, Tata AM, Ferrari D, Cutruzzolà F, Mazzoccoli G, Ziviani E, Pennuto M, Vescovi AL, Rosati J. “Retinoic acid-induced 1 gene haploinsufficiency alters lipid metabolism and causes autophagy defects in Smith-Magenis syndrome.” (2022) Cell Death Dis Nov 21;13(11):981. doi: 10.1038/s41419-022-05410-7. PMID: 36411275

6. Trivieri N, Visioli A, Mencarelli G, Cariglia MG, Marongiu L, Pracella R, Giani F, Soriano AA, Barile C, Cajola L, Copetti M, Palumbo O, Legnani F, DiMeco F, Gorgoglione L, Vescovi AL, Binda E. Growth factor independence underpins a paroxysmal, aggressive Wnt5aHigh/EphA2Low phenotype in glioblastoma stem cells, conducive to experimental combinatorial therapy. J Exp Clin Cancer Res. 2022 Apr 12;41(1):139. doi: 10.1186/s13046-022-02333-1. PMID: 35414102

7. Sisti D, Pazienza V, Piccini F, Citterio B, Baffone W, Donati Zeppa S, Biavasco F, Prospero E, De Luca A, Artico M, Taurone S, Minelli A, Perri F, Binda E, Pracella R, Santolini R, Amatori S, Sestili P, Rocchi MBL, Gobbi P.A proposal for the reference intervals of the Italian microbiota "scaffold" in healthy adults. Sci Rep. 2022 Mar 10;12(1):3952. doi: 10.1038/s41598-022-08000-x. PMID: 35273317

8. Panebianco C, Trivieri N, Villani A, Terracciano F, Latiano TP, Potenza A, Perri F, Binda E, Pazienza V: “Improving Gemcitabine Sensitivity in Pancreatic Cancer Cells by Restoring miRNA-217 Levels” (2021) Biomolecules Apr 26; 11(5):639. doi: 10.3390/biom11050639. PMID: 33925948.

9. Rueca M, Fontana A, Bartolini B, Piselli P, Mazzarelli A, Copetti M, Binda E, Perri F, Gruber CEM, Nicastri E, Marchioni L, Ippolito G, Capobianchi MR, Di Caro A, Pazienza V: “Investigation of Nasal/Oropharyngeal Microbial Community of COVID-19 Patients by 16S rDNA Sequencing” (2021) Int J Environ Res Public Health. Feb 23;18(4):2174. doi: 10.3390/ijerph18042174.PMID: 33672177.

10. Trivieri N, Panebianco C, Villani A, Pracella R, Latiano TP, Perri F, Binda E*, Pazienza V* These authors share the senior authorship: “High Levels of Prebiotic Resistant Starch in Diet Modulate a specific pattern of miRNAs Expression Profile associated to a better overall survival in Pancreatic Cancer” (2020) Biomolecules. Dec 29;11(1):26. doi: 10.3390/biom11010026. PMID: 33383727

11. Trivieri N, Pracella R, Cariglia MG, Panebianco C, Parrella P, Visioli A, Giani F, Soriano AA, Barile C, Canistro G, Latiano TP, Dimitri L, Bazzocchi F, Cassano D, Vescovi AL, Pazienza V, Binda E: "BRAFV600E Mutation Impinges on Gut Microbial Markers Defining Novel Biomarkers for Serrated Colorectal Cancer Effective Therapies (2020) J Exp Clin Cancer Res. Dec14; 39(1):285. doi 10.1186/s13046-020-01801-w. PMID: 33317591.

12. Fontana A, Panebianco C, Picchianti-Diamanti A, Laganà B, Cavalieri D, Potenza A, Pracella R, Binda E, Copetti M, Pazienza V.: “Gut Microbiota Profiles Differ among Individuals Depending on Their Region: An Italian Pilot Study”. Int J Environ Res Public Health. 2019 Oct 23;16(21):4065. doi: 10.3390/ijerph16214065.PMID: 31652705.

13. Mazzini L, Gelati M, Profico DC, Sorarù G, Ferrari D, Copetti M, Muzi G, Ricciolini C, Carletti S, Giorgi C, Spera C, Frondizi D, Masiero S, Stecco A, Cisari C, Bersano E, De Marchi F, Sarnelli MF, Querin G, Cantello R, Petruzzelli F, Maglione A, Zalfa C, Binda E, Visioli A, Trombetta D, Torres B, Bernardini L, Gaiani A, Massara M, Paolucci S, Boulis NM, Vescovi AL: ” (2019) Stem Cells Transl Med. Sep;8(9):887-897. doi: 10.1002/sctm.18-0154.PMID: 31104357.

14. Visioli A*, Giani F, Trivieri N, Pracella R, Miccinilli E, Cariglia MG, Palumbo O, Arleo A, Dezi F, Copetti M, Cajola L, Restelli S, Papa V, Sciuto A, Latiano TP, Carella M, Amadori D, Gallerani G, Ricci R, Alfieri S, Pesole G, Vescovi AL, Binda E: “Stemness underpinning all steps of human colorectal cancer defines the core of effective therapeutic strategies” (2019) EBioMedicine May 2 pii: S2352-3964(19)30288-9. doi: 10.1016/j.ebiom.2019.04.049. PMID: 31056474.

15. Zalfa C, Rota Nodari L, Vacchi E, Gelati M, Profico D, Boido M, Binda E, De Filippis L, Copetti M, Garlatti V, Daniele P, Rosati J, De Luca A, Pinos F, Cajola L, Visioli A, Mazzini L, Vercelli A, Svelto M, Vescovi AL, Ferrari D: “Transplantation of clinical-grade human neural stem cells reduces neuroinflammation, prolongs survival and delays disease progression in the SOD1 rats” (2019) Cell Death Dis Apr 25;10(5):345. Doi: 10.1038/s41419-019-1582-5. PMID: 31024007.

16. Rosati J, Ferrari D, Altieri F, Tardivo S, Ricciolini C, Fusilli C, Zalfa C, Profico D, Pinos F, Bernardini L, Torres B, Manni I, Piaggio G, Binda E, Copetti M, Lamorte G, Mazza T, Carella M, Gelati M, Valente EM, Simeone A, Vescovi AL: “Establishment of stable iPS-derived human neural stem cell lines suitable for cell therapies” (2018) Cell Death Dis Sep 17;9(10):937. Doi: 10.1038/s41419-018-0990-2- PMID: 30224709

17. Scicchitano BM, Sorrentino S, Proietti G, Lama G, Dobrowolny G, Catizone A, Binda E, Larocca LM, Sica G: “Levetiracetam enhances the temozolomide effect on glioblastoma stem cell proliferation and apoptosis” (2018) Cancer Cell Int Sep 10;18:136. doi: 10.1186/s12935-018-0626-8. PMID:30214378

18. Angelucci C, D’Alessio A, Lama G, Binda E, Mangiola A, Vescovi A, Proietti G, Masuelli L, Bei R, Fazi B, Ciafrè SA, Sica G: “Cancer stem cells from peritumoral tissue of glioblastoma multiforme: the missing link between tumor development and progression?” (2018) Oncotarget Jun 15;9(46): 28116-28130. doi: 10.18632/oncotarget.25565 PMID:29963265

19. Binda E*, Visioli A, Giani F, Trivieri N, Palumbo O, Restelli S, Dezi F, Mazza T, Fusilli C, Legnani F, Carella M, Di Meco F, Duggal R, Vescovi AL: “Wnt5a drives an invasive phenotype in human glioblastoma stem-like cells” (2017) Cancer Research Feb 15; 77(4):996-1007 doi: 10.1158/0008-5472.CAN-16-1693 PMID: 28011620. *co-corresponding author

20. Lama G, Mangiola A, Proietti G, Colabianchi A, Angelucci C, D’Alessio A, De Bonis P, Geloso MC, Lauriola L, Binda E, Biamonte F, Giuffrida MG, Vescovi A, Sica G: “Progenitor/stem cells markers in brain adjacent to glioblastoma: GD3 ganglioside and NG2 proteoglycan expression” (2016) J Neuropathol Exp Neurol Jan 20 pii: nlv012 PMID: 26792897

21. Mazzini L, Gelati M, Profico DC, Sgaravizzi G, Projetti Pensi M, Muzi G, Ricciolini C, Rota Nodari L, Carletti S, Giorgi C, Spera C, Domenico F, Bersano E, Petruzzelli F, Cisari C, Maglione A, Sarnelli MF, Stecco A, Querin G, Masiero S, Cantello R, Ferrari D, Zalfa C, Binda E, Visioli A, Trombetta D, Novelli A, Torres B, Bernardini L, Carriero A, Prandi P, Servo S, Cerino A, Cima V, Gaiani A, Nasuelli N, Massara M, Glass J, Sorarù G, Boulis NM, Vescovi AL: “Human Neural stem cell transplantation in ASL: initial results from phase I trial” (2015) J Transl Med Jan 27; 13:17. doi: 10.1186/s12967-014-0371-2. PubMed PMID: 25889343

22. Vescovi AL, Binda E, Mazza T, Dimeco F: “Ephrina2 receptor in human glioblastoma cancer stem cells and identification of new, putative therapeutic targets.” Neuro Oncol. (2014). Suppl 3:iii34. doi: 10.1093/neuonc/nou208.42

23.Meco D, Servidei T, Lamorte G, Binda E, Arena V, Riccardi R: “Ependymoma stem cells are highly sensitive to temozolomide in vitro and in orthotopic models” (2014) Neuro Oncol Feb 12. doi: 10.1093/neuonc/nou008PubMed PMID: 24526307

24. Fusar Poli E, Zalfa C, D’Avanzo F, Tomanin R, Carlessi L., Bossi M, Rota Nodari L, Binda E, Marmiroli P, Scarpa M, Delia M, Vescovi AL, De Filippis L: “Murine neural stem cells model Hunter disease in vitro: glial cell-mediated neurodegeneration as a possible mechanism involved” (2013) Cell Death Dis 7;4:e906. doi: 10.1038/cddis.2013.430

25. Duggal R, Geissinger U, Zhang Q, Aguilar J, Chen NG, Binda E, Vescovi AL, Szalay AA: “Vaccinia virus expressing bone morphogenetic protein-4 in novel glioblastoma orthotopic models facilitates enhanced tumor regression and long-term survival” (2013) J Transl Med 24;11(1):155.doi:10.1186/1479-5876-11-155. (Epub ahead of print) PubMed PMID: 23800258

26. Binda E*, Visioli A, Giani F, Lamorte G, Copetti M, Pitter KL, Huse JT, Cajola L, Zanetti N, DiMeco F, De Filippis L, Mangiola A, Maira G, Anile C, De Bonis P, Reynolds BA, Vescovi AL: “The EphA2 receptor drives self-renewal and tumorigenicity in stem-like tumor propagating cells from human glioblastomas” (2012). Cancer Cell 22(6):765-80. doi: 10.1016/j.ccr.2012.11.005. PubMed PMID: 23238013. *co-corresponding author

Review
    1. Binda E, Reynolds BA, Vescovi AL: “Glioma stem cells: turpis omen in nomen? (The evil in the name)” (2014). J Intern Med Apr 7. doi: 10.1111/joim.12254. PubMed PMID: 24708237
    2. De Filippis L, Binda E: “Concise review: self-renewal in the central nervous system: neural stem cells from embryo to adult” (2012). Stem Cells Transl Med 1(4):298-308. doi: 10.5966/sctm.2011-0045. PubMed PMID: 23197809
    3. Binda E, Visioli A, Reynolds BA, Vescovi AL: “Heterogeneity of cancer-initiating cells within glioblastoma” (2012). Front Biosci (Schol Ed) 1;4:1235-48. PubMed PMID: 22652868

BOOK Chapter
    1. Peréz JA, Garcia-Aloy M, Cariglia MG, Binda E, Pazienza V, Rubert J: ”Exploiting intestinal organoids and foodomics strategies for studying the role of diet and host responses” (2020) Reference Module in Food Science. Doi 10.1016/B978-0-08-100596-5.22887-4.
    2.Binda E, Visioli A, Trivieri N, Vescovi AL: “Drug delivery in an orthotopic tumor stem cell-based model of human glioblastoma” (2019) Methods Mol Biol 1869:197-205. Doi: 10.1007/978-1-4939-8805-1_17. PMID: 30324525.