Pediatric Onco-Hematology
- To provide comprehensive, high-quality care to children with hematological and oncological conditions, in alignment with international treatment protocols;
- To perform hematopoietic stem cell transplantation;
- To deliver state-of-the-art immunotherapy in accordance with the latest standards upheld by leading Italian and European pediatric onco-hematology centers;
- To utilize cutting-edge laboratory techniques for the accurate diagnosis and monitoring of oncological conditions;
- To offer robust supportive therapies for both the child and their family, including psychological assistance;
- To implement surveillance protocols both during and after treatment.
The Pediatric Onco-Hematology Unit is located on the 3rd floor of the “Giovanni Paolo II” Outpatient Clinic on Viale Padre Pio.
Unit Structure:
The Inpatient Ward is situated on the 3rd floor of the outpatient clinic and includes 9 single-occupancy rooms, each designed to accommodate the patient and an accompanying parent. All rooms are equipped with Wi-Fi internet access.
In compliance with current pandemic-related regulations, the common area offers access to a fully equipped kitchen with appliances, a washing machine, a dryer, a playroom for younger children, and a Teen Zone with spaces for music, reading, and video games for adolescent patients.
During inpatient care, a full range of diagnostic and therapeutic procedures is available, including first- and second-level evaluations (e.g., bone marrow aspiration, bone marrow biopsy, imaging studies), which can be performed under sedation if necessary. These procedures support the diagnosis and treatment of onco-hematological disorders.
Treatments provided include: Chemotherapy; Immunotherapy; Intravenous immunoglobulin therapies; Transfusion-based supportive therapies; Any other care required for the patient’s condition.
Access to the Ward is arranged following direct consultation with the ward’s physicians via +39 0882 416250 or after an outpatient evaluation at our Day Hospital/Clinic, where hospitalization may be recommended.
The Hematopoietic Stem Cell Transplant Section has successfully conducted more than 130 transplant procedures to date. Patients are managed by a specialized team during both the preparatory phase, which includes pre-transplant assessments, and the transplant phase itself, focusing on the management of potential complications. Additionally, a dedicated outpatient clinic is available to support transplanted patients.
The services offered in the Day Hospital/Outpatient Clinic include:
- Initial pediatric onco-hematology consultation;
- Chemotherapy administration;
- Immunotherapy;
- Immunoglobulin infusions;
- Drug and antibiotic infusions;
- Transfusion support (plasma, platelets, packed red blood cells);
- Care, dressing, and heparinization of all types of central venous catheters;
- Nutritional support (enteral and parenteral nutrition);
- Peripheral blood smear analysis;
- Follow-up evaluations for monitoring treatment-related side effects and assessing relapse risk.
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In updating
The Pediatric Onco-Hematology Unit (OEPED) specializes in the diagnosis, treatment, and follow-up of onco-hematological diseases in children and adolescents, including:
Myelo-lymphoproliferative disorders
- Acute and chronic leukemias
- Myelodysplastic syndromes
- Hodgkin and non-Hodgkin lymphomas
Diagnosis and treatment of solid tumors
- Brain and central nervous system tumors
- Soft tissue and bone sarcomas
- Neuroblastoma
- Wilms tumor and other kidney tumors
- Germ cell tumors
- Retinoblastoma
- Langerhans cell histiocytosis
- Other rare tumors
Diagnosis and treatment of hematological and lymphatic disorders
- Congenital and acquired anemias
- Bone marrow aplasia
- Thalassemias and hemoglobinopathies
- Acute and chronic thrombocytopenia
- Congenital platelet disorders
- Coagulation disorders
- Hemolytic anemias
- Lymphadenopathies
- Thrombocytosis
- Primary and secondary immunodeficiencies
- Autoimmune Lymphoproliferative Syndrome (ALPS)
- Neutropenia
Facilities and Services Available at the OEPED Ward/Day Hospital
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The AGAPE team, along with numerous volunteers and entertainers, provides engaging activities and games to entertain children during their hospital stay. In 2019, AGAPE inaugurated the “Angels and Dreams” Francesca De Sinno Guest House.
Located approximately 800 meters from the hospital, at the start of Viale Cappuccini, the guest house features: 2 apartments for transplanted patients, 8 double rooms and 1 single room, all with private bathrooms and televisions, offering a total of 21 beds. The guest house provides accommodation for children and adults undergoing onco-hematological treatment.
Clown therapy has been an integral component of the treatment process in our unit since 2004.
Casa Zeni managed by the “Casa Sollievo della Sofferenza” Foundation, is a residence for children receiving treatment at the Pediatric Onco-Hematology Ward/Day Hospital and their families.

Head of Operative Unit:
Dr.ssa Anita Sprito
Operative Unit Contacts
Administration: 0882 416602 fax 0882 416319
Nurses’ Station: 0882 416253
Physicians’ Office: Phone/fax 0882 416250
Hematopoietic Stem Cell Transplant Center
0882 416254
Laboratorio Specialistico di Citologia oncoematologica
0882 416251
Specialized Laboratory for Onco-Hematological Cytology
Physicians’ Office: 0882 416249
Nursing Station: 0882 416248
School
0882 416238
Secretariat
0882 416600
Medical Sciences Department
Doctors




























